Abstract:
Cholinesterases play an important role in the area of neurobiology, toxicology, and
pharmacology, out of which acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)
are vital in nerve impulse transmission [1]. The enzyme AChE catalyzes the hydrolysis of the
ester bond of acetylcholine to terminate the nerve impulse transmission at the cholinergic
synapses [2]. Compounds that are capable of suppressing the activity of AChE are known as
AChE inhibitors or anticholinesterases. Anticholinesterases inhibit AChE enzyme, thereby ......