Jeyadevan, J.P.; Bray, B.G.; Chadwick, J.; Mercer, A.E.; Byrne, A.; Ward, S.A.; Park, B.K.; Williams, A.P.; Cosstick, R.; Davies, J.; Higson, A.P.; Irving, E.; Posner, G.H.; Neill, P.M
(American Chemical Society, 2004-02-26)
Four series of C-10 non-acetal dimers were prepared from key trioxane alcohol 10β-(2-hydroxyethyl)deoxoartemisinin (9b). All of the dimers prepared displayed potent low nanomolar antimalarial activity versus the K1 and HB3 ...