Abstract:
Diabetes mellitus is becoming a metabolic disease that is defined by
the level of hyperglycemia. Nowadays, it has a serious threat to
public healthiness in throughout the world. Constituents and
extracts isolated from diverse natural resources, mainly plants, have
constantly been a rich store for controlling and treating diabetes
problems. Numerous researches are ongoing to identify the suitable
traditional medical drugs, medicinal herbs, and resources for
managing this condition. Murraya koenigii Spreng (family Rutaceae)
is commonly known as a ‘curry leaf tree’ locally. It is widely
scattered in India and Sri Lanka, and leaves are commonly used for
cooking. And also mainly used for various health conditions such as
diabetes, anemia, diarrhea, and others. The present review aimed to
critically review the anti-hyperglycemic effect of the M. koenigii
based on the review, in vitro, in vivo, and clinical studies. Based on
this review, the M. koenigii possess flavonoids, phenols, saponins,
alkaloids, tannins, and cardiac glycosides. It has shown a potential
anti-hyperglycemic effect on induced diabetic rats. This review
reported the potential of M. koenigii and its extract to be a high-value
dietary product in terms of its anti-hyperglycemic effects and
industrial profits. Therefore, the present review supports the
researchers and readers/users to realize the importance of using M.
koenigii in managing diabetes mellitus. Further, this review provides
a valuable document for future scientific-related clinical trials in
diabetic patients.
