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A preliminary study on the toxic effects of an emerging detergent (Prinso) on rat skin

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dc.contributor.author Dayasiri, P. B. I. A. K.
dc.contributor.author Chandana, E. P. S.
dc.date.accessioned 2021-02-17T23:01:48Z
dc.date.accessioned 2022-07-11T06:37:33Z
dc.date.available 2021-02-17T23:01:48Z
dc.date.available 2022-07-11T06:37:33Z
dc.date.issued 2011
dc.identifier.citation Dayasiri, P. and Chandana, E., 2012. A preliminary study on the toxic effects of an emerging detergent (Prinso) on rat skin. Vingnanam Journal of Science, 10(1), pp.19–24. DOI: http://doi.org/10.4038/vingnanam.v10i1.4074
dc.identifier.issn 2012-9939
dc.identifier.uri http://repo.lib.jfn.ac.lk/ujrr/handle/123456789/1552
dc.description.abstract Toxic effects of household detergents on human skin have been reported previously. Recently emerged detergent “PRINSO” is extensively gaining popularity in many areas of Sri Lanka. “PRINSO” is also sold under other trade names such as “Ever Light”, “Vihanga” and “Diamond Light”. The product contains 2 sachets, one containing pink crystals (potassium permanganate) and the other containing white crystals (oxalic acid). Several cases have been reported on deliberate intoxication of “PRINSO” in order to commit suicide. Nevertheless, effect of “PRINSO” exposure on mammalian skin has not been reported. These observations prompted us to study the effects of “PRINSO” exposure (short-term) on mammalian skin. Twenty eight rats were randomly selected. In all rats, 4 cm2 area of skin was shaved on dorsal area just behind the neck. Rats were randomly assigned into four groups in which each group consisted of seven rats. Each group was randomly assigned for the treatments of distilled water, “PRINSO” and other two detergents namely “TIDE” and “SUNLIGHT”. Each shaved skin patch of the rats was treated with 5 ml of respective detergent solutions. Lesions were appeared after two days in the subjects where “PRINSO” solution was applied. Lesions were completely cured after 12 to 20 days. There were no detectable lesions in the groups treated with distilled water, “TIDE” and “SUNLIGHT”. These data indicates the primary toxic effects of “PRINSO” exposure on rat skin. Therefore effects of “PRINSO” on human skin should be tested rigorously. en_US
dc.language.iso en en_US
dc.publisher Faculty of Science, University of Jaffna
dc.subject Detergents en_US
dc.subject PRINSO en_US
dc.subject Rats en_US
dc.subject Skin lesions en_US
dc.title A preliminary study on the toxic effects of an emerging detergent (Prinso) on rat skin en_US
dc.type Article en_US


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