Abstract:
The Siddha system of medicine is purely scientific and the peculiar complex system of science and
philosophy. Fourier Transform Infrared Spectroscopy (FTIR) is certainly one of the most important
analytical techniques for herbo mineral medicine. FTIR can be implemented during herbal drug
development in production for process monitoring or in quality control laboratories. The aim of study
is to evaluate the morphology and elemental characterization of the Neer Perukki Chooranam. The
functional groups of their formulations are analyzed through FTIR spectroscopy and the biological
roles of the functional groups are discussed in this study. The raw drugs is collected and purified as
per Siddha literature. Drug Neer Perukki Chooranam, which has been illustrated in the Pharmacopeia
of Indian Medicine for the management of Neerkattu, Soabai and Makotharam. The Fourier
Transform Infrared Spectroscopy compounds show 13 functional groups. There are O-H Stretching
(Alcohol), C-H Stretching (Alkane),O=C=O Stretching(Carbon dioxide),C-C bending, (Alkene),O-H
bending(Carboxylic acid),C-O Stretching(Aromatic ester),C-O Stretching (Tertiary alcohol), S=O
Stretching (Sulfoxide), C-H bending (1,2-disubstituted) and C-1 Stretching (Halo compound)which
ensures the therapeutic effect of the drug. The instrumental analysis FTIR study of Neer Perukki
Chooranam is the presence of functional groups through the stretch and bends which is responsible
for its functional activity. The functional groups in Neer Perukki Chooranam has diuretic activity.
According to the FTIR analysis, the research drug “Neer Perukki Chooranam” is very effective for
the indications of Neerkattu, Soabai and Makotharam.
