Abstract:
Disorders in human Genetics impact their reproductive
potential in several ways such as fertility, retaining
fertility and fertility treatment outcomes. However,
alterations in genes might be harmless or can bring
about detrimental outcomes. Understanding the impact
of genetics on reproduction is essential to have better
fertility outcomes. An individualized assessment of
a couple to identify the underlying aetiology related
to genetic problems along with genetic testing is
considered the first step of the solution. Moreover,
assisted reproductive technologies (ART) are a possible
fertility treatment option to address feasible genetic
problems even before the establishment of pregnancy.
A pre-ART assessment of a couple with potential
genetic problems can be carried out with expanded
carrier screening and genetic analysis of the gametes
and embryo during the ART procedure to detect
abnormalities and select a healthy embryo are play an
indispensable role to overcome this puzzle.