Abstract:
In this work, we propose and demonstrate a carbon nanotube (CNT) field-effect transistor (FET) based
biosensor for selective detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
CNT FETs were fabricated on a flexible Kapton substrate and the sensor was fabricated by immobilizing
the reverse sequence of the RNA-dependent RNA polymerase gene of SARS-CoV-2 onto the CNT channel.
The biosensors were tested for the synthetic positive and control target sequences. The biosensor showed
a selective sensing response to the positive target sequence with a limit of detection of 10 fM. The
promising results from our study suggest that the CNT FET based biosensors can be used as a diagnostic
tool for the detection of SARS-CoV-2.
2021 Elsevier Ltd. All rights reserved.
Selection and peer-review under responsibility of the scientific committee of the Indo-UK International
Virtual Conference on Advanced Nanomaterials for Energy and Environmental Applications (ICANEE 2020). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/
licenses/by-nc-nd/4.0/).
