Abstract:
Acanthosis nigricans is strongly associated with
obesity and insulin resistance. This cross-sectional
analytical hospital-based study is conducted to access
the Association Between Acanthosis Nigricans (AN)
and cardiometabolic risk among overweight and obese
patients aged 18 and above admitted to medical wards
of Teaching Hospital Jaffna. Data were entered and
analysed using Statistical Packages for social sciences
(SPSS) version 21.
Out of the 230 overweight and obese patients 74.8% had
AN. Patients with AN had a higher mean BMI value of
29.65 suggesting that significant percentage of patients
with AN are obese rather than being overweight. Higher
prevalence of AN among females were noted. Presence
of skin tags revealed an important association with AN.
Most of the participants had central obesity regardless
whether they were overweight or obese.
Even though statistically insignificant, individuals
with AN had increased likelihood of having metabolic
syndrome and associated with smokers. A significant
association between Sagittal Abdominal Diameter(SAD)
and presence of AN were noted. The mean of sagittal
circumference in those with AN and those without
respectively are 22.02 and 20.43. In conclusion AN is
strongly associated with higher BMI (Obesity), higher
waist circumference and higher sagittal abdominal
diameter and metabolic syndrome and smoking
demonstrated a strong association with AN.
