Performance of New Aminothiazole Schiff Base Sensor for Cation Detection

Abstract

The 2-hydroxybenzaldehyde-2-aminothiazole ligand was synthesized from benzaldehyde and 2-aminothiazole by direct condensation method using methanol as solvent. The formation of 2-hydroxybenzaldehyde-2- aminot hiazole compound was confirmed by FTIR, 13C NMR, 1H NMR and mass spectrometry. The band at 1658.78 cm-1 confirms the presence of C=N group. The total number of carbon atoms was confirmed by 13C NMR. The chemical shifts (100 MHz, DMSO:d6, ppm) were noticed at (C1-130.14), (C2-122.72), (C3-128.32), (C4-117.70), (C5-154.62), (C6-128.53), (C7-140.48), (C8-139.36), (C9-128.96) and (C10-129.07). The total number of hydrogen atoms was confirmed by 1H NMR .The chemical shifts of 1H NMR (400 MHz, DMSO: d6, ppm) were noticed at (1H-6.857), (2H-6.945), (3H-6.964), (4H-6.983), (5H-6.993), (6H-7.013), (7H-7.126), (8H-7.157) and (OH-9.237). The molecular mass of the compound was confirmed by mass spectrometry and found to be m/z=204.23 and the molecular formula of the compound was C10H8N2SO. The synthesized compound was investigated for chemosensor application. The synthesized ligand was complexed with various metal ions like Na+, K+, Ba2+, Ca2+, Mg2+, Ag+, Cu2+, Co2+, Cd2+, Cr3+, Fe2+, Fe3+, Hg2+, Ni2+, Mn2+, Zr2+, Zn2+, Pb2+, Al3+ and Ce2+ and extent of complexation of the metals with the ligand was analysed using absorption and emission spectroscopy. The 2-hydroxybenzaldehyde-2-aminothiazole was analysed for high selectivity & sensitivity towards a particular metal ion. The compound was further studied for its performance on antibacterial, and antifungal activities.