http://repo.lib.jfn.ac.lk/ujrr/handle/123456789/11012 2026-04-07T13:49:10Z 2026-04-07T13:49:10Z Kumarasinghe, P.B.W.S.R. Ekanayake, E.M.P. Napagoda, N.A.D.N. http://repo.lib.jfn.ac.lk/ujrr/handle/123456789/11040 2025-01-28T04:19:03Z 2024-01-01T00:00:00Z

Title: Survival Analysis of Primary Biliary Cirrhosis Patients Authors: Kumarasinghe, P.B.W.S.R.; Ekanayake, E.M.P.; Napagoda, N.A.D.N. Abstract: Primary Biliary Cirrhosis (PBC) is a dreadful rare disease as it affects an important human organ, the liver. This study was conducted by survival analysis on Primary Biliary Cirrhosis patients in the United States using prerecorded data from 310 patients who were suffering from PBC. The Follow-up time, Status at the end, and seventeen other factors were analyzed statistically to identify the risk factors for Primary Biliary Cirrhosis. Baseline characteristics were calculated and a nonparametric model (Kaplan Meier), a semi-parametric model (Cox Proportional Hazards), and two parametric models (Exponential and Weibull) were developed for analyzing mortality and survival appropriately. Area under the Receiver Operator Characteristics curve was used for comparing the four models and the model which produced the highest Area under the Receiver Operator Characteristics curve was identified as the best fitted model. A nomogram was constructed for the graphical prediction of mortality or survival appropriately. Baseline characteristics showed that Age, Serum Bilirubin, Albumin, Urine Copper, Alkaline Phosphatase, SGOT level, Platelets, Prothrombin Time, Presence of Ascites, Presence of Hepatomegaly, Presence of Spiders, Presence of Edema, and Histologic Stage of Disease are significant factors on PBC. The Cox Proportional Hazards model could be identified as the best-fitted model from among the four fitted models, according to which Age, Serum Bilirubin, Albumin, and Urine Copper were the risk factors of Primary Biliary Cirrhosis. Moreover, Age and Serum Bilirubin were the most significant risk factors as they emerged in all fitted models.

2024-01-01T00:00:00Z Arivalzahan, S. Nuwan Kumara, D. http://repo.lib.jfn.ac.lk/ujrr/handle/123456789/11038 2025-01-28T04:17:06Z 2024-01-01T00:00:00Z

Title: Ranking Sri Lankan Universities Based on Study Program Cut-offs Authors: Arivalzahan, S.; Nuwan Kumara, D. Abstract: Since 2015, the University Grants Commission has been releasing separate district-wise cut-off Zscores for various universities across different study programs. This allows for a comparison of universities based on student preferences for each program. However, there hasn't been much statistical study conducted on these cut-off Z-scores. The primary aim of this research is to statistically analyze the cut-off Z-scores for the engineering and medical faculties and rank those faculties based on the preferences of G.C.E. (A/L) students. The sample comprises cut-off Z-scores from 2015 to 2021. The average cut-off Z-scores across the 25 districts are calculated for these two study programs. For this analysis, the one-way analysis of variance and linear regression analysis techniques have been employed. The study's results indicate significant differences among universities for both study programs. Further analysis using the Least Significant Difference test has been utilized to rank the universities for both study programs. The University of Colombo is ranked as the most demanding university for medicine, while the University of Moratuwa is ranked as the most demanding university for the engineering program. It appears that students generally prefer universities located closer to the capital city, Colombo. Moreover, the study reveals a significant positive correlation between the cut-off Z-scores and the years for the medicine study program. This suggests that the competition for admission to medicine has intensified over the years.

2024-01-01T00:00:00Z Dilini Jayaweeraa, D. Dargentolleb, C. Kuganathanc, S. http://repo.lib.jfn.ac.lk/ujrr/handle/123456789/11037 2025-01-28T04:15:16Z 2024-01-01T00:00:00Z

Title: Nutritional composition and fatty acid profile of Yellowfin Tuna (Thunnus albacares) by-products in Sri Lanka Authors: Dilini Jayaweeraa, D.; Dargentolleb, C.; Kuganathanc, S. Abstract: The present study evaluated the nutritional composition and fatty acid profile of juvenile yellowfin tuna (n = 12, mean weight = 0.875 ± 0. 107 kg) heads, dorsal skins, and caudal muscles with fins. Fatty acid methyl esters (FAME) were separated by gas chromatography (Varian 3900 GC). The highest protein content was obtained in the caudal muscles with fins (23.80 ± 0.14 %) and the lowest (18.75 ± 0.21 %) as reported in the yellowfin tuna head. The highest moisture content was recorded in the caudal muscles with fins (77.06 ± 0.31%). The ash content was comparatively higher (8.65 ± 0.78%) in yellowfin tuna heads than in the dorsal and caudal muscles. The highest fat content was recorded in yellowfin tuna heads (4.18 ± 0.33%) which could be a potential source for fish oil extraction. The most abundant fatty acids in by-products were identified as docosahexaenoic poly-unsaturated fatty acid (DHA/PUFA) (head: 26.63 ± 0.19%, dorsal: 34.71 ± 0.72%, caudal: 31.27 ± 0.90%), followed by saturated fatty acids; palmitic acid (SFA) (head: 22.52 ± 0.22%, dorsal: 20.14 ± 0.47%, caudal: 20.72 ± 0.20%). The results of the present study indicate that omega-3 PUFAs ranged from 35.12% to 42.93% and were higher than omega-6 PUFAs ranging from 4.15% to 4.74% in yellowfin tuna heads, dorsal skin, and caudal muscles. The nutritional composition and fatty acid profile revealed that the yellowfin tuna by-products are excellent sources for extracting omega-3 fatty acids and protein for the food and pharmaceutical industries in Sri Lanka.

2024-01-01T00:00:00Z Chanaka Supun Bandara Pallemulla, P.M.R. Kuganathan, S. Santos, J. Jayasinghe, P. http://repo.lib.jfn.ac.lk/ujrr/handle/123456789/11034 2025-01-28T04:12:34Z 2024-01-01T00:00:00Z

Title: Length-Weight relationship and Condition Factor of Sardinella gibbosa (Bleeker, 1849) from the North-West Coast of Sri Lanka Authors: Chanaka Supun Bandara Pallemulla, P.M.R.; Kuganathan, S.; Santos, J.; Jayasinghe, P. Abstract: The present study aimed to determine the length-weight relationship and condition factor of Sardinella gibbosa (Bleeker, 1849) on the North-West coast of Sri Lanka. The samples were collected every month from three major fish landing centers between 2021-2023. The fish were caught in a small mesh (1.27 cm - 3.81 cm) gill net. The average weight of S. gibbosa ranged from 4.2 g to 28.1 g, with a mean of 15.77 g. The length ranged from 6.2 cm to 14.3 cm, with an average of 9.65 cm. The length-weight relationship, W=aLb and condition factor (W *100/L3) are presented for the S. gibbosa. The length-weight relationship of the sardines collected from Chilaw, Negombo, and Puttalam sampling areas were W=0.11328L2.085 (R2=0.7208), W=0.0927L2.3319 (R2=0.7667), and W=0.0926L2.3562 (R2=0.7586), respectively. The condition factor ranged from 1.467 to 1.484 and the regression coefficient indicated negative allometric growth. The data obtained can be used as a baseline for future studies and valuable source for fisheries managers, biologists, and conservationists to save the fisheries resources.

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